ZAP-70 Analysis by Flow Cytometry
Test Mnemonic
ZAP70
CPT Codes
- 88184 - QTY (1)
- 88185 - QTY (1)
LOINC ®
46722-5
Aliases
- Zeta-chain Associated Protein
Includes
- VIABILITY
- ZAP70+/CD19+
Performing Laboratory
Quest SJC
FDA Category
Analyte Specific Reagent
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Whole blood | EDTA (Lavender) | Ambient | Send to Cleveland Clinic Laboratories ASAP on the day of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Whole blood | Sodium heparin (Green) | Ambient | Send to Cleveland Clinic Laboratories ASAP on the day of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 72 hours |
| Frozen | Unacceptable |
| Refrigerated | Unacceptable |
Days Performed
Sun - Sat
Turnaround Time
5 - 6 days
Reference Range
| ZAP70+/CD19+ | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <10 | % |
Special Info
Ship blood at room temperature. Grossly hemolyzed specimens will be rejected. Yellow top ACD B tubes are not acceptable.
Clinical Info
Patients with chronic lymphocytic leukemia have variable outcomes; ZAP-70 can predict patients who have aggressive disease and need aggressive therapy.