Tumor Necrosis Factor
Test Mnemonic
TNFA2
CPT Codes
- 83520 - QTY (1)
LOINC ®
3074-2
Aliases
- TNF
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Frozen, Critical | Critical Frozen. Separate serum from cells ASAP or within 2 hours of collection. Transfer into standard aliquot tube and freeze. Additional specimens must be submitted when multiple tests are ordered. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Frozen, Critical | Critical Frozen. Separate serum from cells ASAP or within 2 hours of collection. Transfer into standard aliquot tube and freeze. Additional specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.4 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 30 minutes |
| Refrigerated | After separation from cells: Unacceptable |
| Frozen | After separation from cells: 1 year |
Days Performed
Sun - Sat
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Quantitative Multiplex Bead Assay |
Reference Range
| Tumor Necrosis Factor - alpha, Serum | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < = 7.2 | pg/mL |
Special Info
CRITICAL FROZEN. Additional specimens must be submitted when multiple tests are ordered. Refrigerated, contaminated or heat-inactivated specimens are unacceptable. This test is New York DOH approved.
Clinical Info
Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day. Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.