Syphilis Treponemal with reflex
Test Mnemonic
SYPHTX
CPT Codes
- 86780 - QTY (1)
Aliases
- T. pallidum
- Treponema pallidum
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
In Vitro Diagnostic
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Submitting the minimum volume will not allow for repeat testing or addons. Required volume of 1 mL is preferred when possible. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 3 days |
| Refrigerated | 7 days |
| Frozen | 30 days |
Days Performed
Mon - Sat
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescent Microparticle Immunoassay (CMIA) |
Reference Range
Special Info
Results in samples from immunosuppressed patients or from patients with disorders leading to immunosuppression should be interpreted with caution.
Clinical Info
This test is recommended as the screen in patients with clinical and/or epidemiological risk factors for contracting syphilis. Final interpretation should take into account the results from RPR and the confirmatory test, where indicated. A nonreactive result does not totally exclude a recent, within the past 2-3 weeks, Treponema pallidum infection. Detection of treponemal antibodies may indicate recent, past, or successfully treated syphilis infections and therefore cannot be used to differentiate between active and cured cases.
Clinical Limitation
Not intended for use in the screening of blood, plasma or tissue donors. Performance has not been established for the use of cadaveric specimens or the use of body fluids (other than serum). Avoid specimens with the following conditions: heat-inactivated, grossly hemolyzed (> 500 mg/dL hemoglobin), grossly lipemic, or obvious microbial contamination.