Plasminogen Activator Inhibitor, Activity
Test Mnemonic
PAI
CPT Codes
- 85415 - QTY (1)
LOINC ®
5975-8
Aliases
- PAI
- Plasminogen Activator Inhibitor 1, Activity
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.5 mL | Plasma | Sodium citrate (Lt. Blue) | Frozen, Critical | Collect specimen between 8:00 a.m. - 12:00 noon. Separate plasma from cells within 1 hour of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 hour |
| Refrigerated | Unacceptable |
| Frozen | 2 months |
Days Performed
Mon, Thu
Turnaround Time
2 - 9 days
Methodology
| Name | Description |
|---|---|
| Bioimmunoactivity |
Reference Range
Special Info
Plasminogen Activator Inhibitor 1 (PAI-1) has diurnal variation, with higher concentration in the morning and decreased concentration in the afternoon. PAI-1 is also an acute phase reactant. The reference interval was established from fasting samples drawn between 8am and 12pm.
Clinical Info
This assay was designed primarily to identify elevated PAI-1 concentrations, which are thought to be a thrombotic risk factor. Concentrations below 2.0 IU/mL are not accurately quantified by this assay. A test result of <2.0 IU/mL is not diagnostic of PAI-1 deficiency and may be seen in normal individuals.