Oxidized Low-density Lipoprotein (LDL)
Test Mnemonic
OXLDL
CPT Codes
- 83520 - QTY (1)
Performing Laboratory
Cleveland HeartLab, Inc.
FDA Category
In Vitro Diagnostic
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Plasma | EDTA (Lavender) | Refrigerated | Draw and gently invert 8 to 10 times. Centrifuge for 10 minutes. Pre-squeeze transfer pipet bulb and draw off approximately 2/3 of the upper plasma layer. Note: This ensures that the buffy coat and red cells remain undisturbed. Transfer plasma into aliquot tube labeled as "EDTA plasma" and cap tightly. Discard original tube and store aliquot tube refrigerated at 2 - 8 C until ready to ship (ship same day). |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | SST (Speckled or Tiger Top) | Refrigerated | Gently invert tube 5 times immediately after draw. Do NOT shake. Allow blood to clot 30 minutes. Centrifuge for 10 minutes. Send specimen in original collection tube. Store refrigerated at 2 - 8 C until ready to ship (ship same day). |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.2 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 7 days |
| Frozen | 28 days at -20 C; 6 months at -70 to -80 C |
| Ambient | Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Special Info
Store plasma or serum at 2 °C to 8 °C after collection and ship the same day. Unacceptable conditions: Specimens other than EDTA plasma or serum, improper labeling, samples not stored properly, samples older than stability limits.
Clinical Info
The oxidized LDL test may be ordered for individuals at low or intermediate risk of metabolic syndrome or cardiovascular disease. Additionally, this test is useful in individuals who have cardiovascular disease and are at risk for an adverse cardiac event. All ages: < 60 U/L low risk, 60 - 69 U/L moderate risk, > or = 70 U/L high risk.