MYD88 L265P Mutation Analysis Bone Marrow
Test Mnemonic
MYD88M
CPT Codes
- 81305 - QTY (1)
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Bone marrow | EDTA (Lavender) | Ambient | Ambient |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Bone marrow- up to 48 hours |
| Refrigerated | Bone marrow- up to 7 days |
| Frozen | Bone Marrow- unacceptable |
Days Performed
3 days per week
Turnaround Time
5 days
Methodology
| Name | Description |
|---|---|
| Droplet Digital Polymerase Chain Reaction (PCR) |
Special Info
Ambient up to 24 hours. Refrigerated up to 7 days.
Clinical Limitation
This test is designed to detect the point mutation c.794T>C, p.L265P in the MYD88 gene. MYD88 L265P mutations are present in the majority of cases of lymphoplasmacytic lymphoma and, less commonly, in other B-cell lymphoproliferative disorders.