Liver Fibrosis, Chronic Viral Hepatitis




Test Mnemonic

HEPFIB

CPT Codes

  • 83883 - QTY (1)
  • 84450 - QTY (1)
  • 84460 - QTY (1)
  • 84520 - QTY (1)
  • 82977 - QTY (1)
  • 81599 alt code - QTY (1)

Aliases

  • Echosens FibroMeter

Includes

  • Alpha-2-Macroglobulin, FibroMeter
  • Alanine Aminotransferase, FibroMeter
  • Aspartate Aminotransferase, FibroMeter
  • Gamma Glutamyl Transferase, FibroMeter
  • Urea Nitrogen, Serum, FibroMeter
  • FibroMeter Platelet Count
  • Fibrometer Prothrombin Index
  • FibroMeter Patient Score
  • CirrhoMeter Patient Score
  • Fibrosis Metavir Classification
  • InflaMeter Patient Score
  • InflaMeter Metavir Classification
  • EER Fibrometer Report
  • FibroMeter Interpretation

Performing Laboratory

ARUP

FDA Category

Laboratory Developed Test


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2.5 mLWhole bloodEDTA (Lavender) RefrigeratedMultiple specimen tubes must be collected for this panel. Fill tube to at least half of fill volume. This tube is for test: Platelet Count (PLTCT).
3 mLSerumSST (Gold) FrozenMultiple specimen tubes must be collected for this panel. Separate serum from cells ASAP or within 2 hours of collection. Transfer serum to standard aliquot tube. This tube is for test: Liver Fibrosis, Chronic Viral Hepatitis (HEPFIB).
1 mLPlasmaSodium citrate (Lt. Blue) Frozen, CriticalMultiple specimen tubes must be collected for this panel. Separate plasma from cells ASAP or within 2 hours of collection. Transfer platelet-poor citrated plasma to standard aliquot tube and freeze. This tube is for test: Liver Fibrosis, Chronic Viral Hepatitis (HEPFIB).

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
Variable    0.3 mL EDTA (Lavender) whole blood; 1.2 mL SST (Gold) serum; 0.5 mL Sodium citrate (Lt. Blue) plasma

Stability

Environmental Condition Description
FrozenWhole blood: Unacceptable; Serum: 2 weeks; Plasma: 2 weeks
RefrigeratedWhole blood: 48 hours; Serum: 1 week; Plasma: Unacceptable
AmbientWhole blood: 24 hours; Serum: 8 hours; Plasma: 24 hours

Days Performed

Tue - Thu

Turnaround Time

2 - 6 days

Methodology

Name Description
Automated Cell Counter 
Electromagnetic Mechanical Clot Detection 
Enzymatic 
Quantitative Nephelometry 
Spectrophotometry (S) 

Reference Range

Special Info

Automated platelet count required. Multiple specimen tubes must be collected for this panel. Hemolyzed specimens will be rejected. This test is New York state approved.

Clinical Info

This test is used to assess for surrogate markers of liver fibrosis in individuals with chronic viral hepatitis. Anticoagulant therapy with warfarin or other anticoagulants that prolong the prothrombin time may affect test results.