Lead, Urine 24 Hour




Test Mnemonic

ULEADQ

CPT Codes

  • 83655 - QTY (1)

Includes

  • Hours Collected
  • Total Volume
  • Creatinine, Urine - per volume
  • Creatinine, Urine - per 24h
  • Lead, Urine - per volume
  • Lead, Urine - per 24h
  • Lead, Urine - ratio to CRT

Performing Laboratory

ARUP

FDA Category

Laboratory Developed Test


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
8 mLUrine, 24-hour (well-mixed)Plastic containerRefrigerate during collection.RefrigeratedHEAVY METALS FORM REQUIRED to meet State Health Department requirements. Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician) and avoid seafood for 48 hours. Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
8 mLUrine, randomPlastic containerN/ARefrigeratedHEAVY METALS FORM REQUIRED to meet State Health Department requirements. Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician) and avoid seafood for 48 hours. Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Ambient1 week
Refrigerated2 weeks
Frozen1 year

Days Performed

Sun - Sat

Turnaround Time

2 - 6 days

Methodology

Name Description
Inductively Coupled Plasma / Mass Spectrometry (ICP-MS) 

Reference Range

Creatinine, 24 - Hour Urine
Sex Age From Age To Type Range Range Unit
Male3 Years8 YearsNormal140 - 700mg/d
Male9 Years12 YearsNormal300 - 1300mg/d
Male13 Years17 YearsNormal500 - 2300mg/d
Male18 Years50 YearsNormal1000 - 2500mg/d
Male51 Years80 YearsNormal800 - 2100mg/d
Male81 Years99 YearsNormal600 - 2000mg/d
Female3 Years8 YearsNormal140 - 700mg/d
Female9 Years12 YearsNormal300 - 1300mg/d
Female13 Years17 YearsNormal400 - 1600mg/d
Female18 Years50 YearsNormal700 - 1600mg/d
Female51 Years80 YearsNormal500 - 1400mg/d
Female81 Years99 YearsNormal400 - 1300mg/d
Lead, per 24h (ug/day)
Sex Age From Age To Type Range Range Unit
       Normal0.0 - 8.1ug/d
Lead, per volume (ug/L)
Sex Age From Age To Type Range Range Unit
       Normal0.0 - 5.0ug/L
Lead, ratio to creatinine (ug/g CRT)
Sex Age From Age To Type Range Range Unit
       Normal0.0 - 5.0ug/g crt

Special Info

HEAVY METALS FORM REQUIRED to meet State Health Department requirements. Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician) and avoid seafood for 48 hours. Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen. Urine transported in a non-trace element-free tube or contaminated with iodine, gadolinium, blood, fecal material or acid preservative will be rejected. This test is New York DOH approved.

Clinical Info

This test may be useful in the assessment of chronic lead exposure or in monitoring chelation therapy. Quantification of urine excretion rates before or after chelation therapy has been used as an indicator of lead exposure. Urinary excretion of >125 mg of lead per 24 hours is usually associated with related evidence of lead toxicity.

Patient Info Sheet