Histoplasma Galactomannan EIA, CSF
Test Mnemonic
HISCSF
CPT Codes
- 87385 - QTY (1)
Includes
- Histoplasma Galactomannan, CSF
Performing Laboratory
ViraCor-IBT Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Cerebrospinal fluid (CSF) | Sterile container | Frozen |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | 3 months (3x freeze/thaw cycles) |
| Refrigerated | 7 days |
| Ambient | 7 days |
Days Performed
Mon - Sat
Turnaround Time
1 - 4 days
Methodology
| Name | Description |
|---|---|
| Immunoenzymatic Assay |
Reference Range
| Histoplasma Galactomannan CSF | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative: <0.2 ng/mL | Positive but below the limit of quantitation: ≥0.2 but <0.8 ng/mL | Positive: ≥0.8 ng/mL |
Special Info
Ship on dry ice for overnight delivery Monday through Friday. This test is New York State approved.
Clinical Info
The clarus Histoplasma Galactomannan EIA is not intended for monitoring therapy. Testing should not be performed as a screening procedure for the general population. The predictive value of a positive or negative result depends on the pretest likelihood of histoplasmosis disease being present. Testing should only be done when clinical evidence suggests the diagnosis of histoplasmosis. Results between different Histoplasma capsulatum assays cannot be compared.
Clinical Limitation
The clarus Histoplasma Galactomannan EIA was found to be cross-reactive with Paracoccidioides, Blastomyces, and some Candida specimens. Positive tests should be confirmed in areas or patient groups where these organisms are endemic or a risk.