Histoplasma Antigen Quantitative by EIA, Serum
Test Mnemonic
SHISTO
CPT Codes
- 87385 - QTY (1)
Includes
- Histoplasma Antigen, Serum
- Histoplasma Antigen, Serum Interp
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | SST (Gold) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.2 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
Days Performed
Mon, Wed, Fri
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Reference Range
Clinical Info
The quantitative range of this assay is 0.19-60.0 ng/mL. Antigen concentrations less than 0.19ng/mL ;greater than 60.0 ng/mL fall outside the linear range of the assay and cannot be accurately quantified. This EIA test should be used in conjunction with other diagnostic procedures, including microbiological culture, histological examination of biopsy samples, serology and/or radiographic evidence, to aid in the diagnosis of histoplasmosis. Cross-reactivity with Blastomyces dermatiditis, Coccidioides immitis, and possibly Talaromyces marneffei have been observed with this EIA. Other clinically and geographically relevant endemic mycoses should be considered in the case of a positive test result.