Histoplasma Ab, CF
Test Mnemonic
HISTCF
CPT Codes
- 86698 - QTY (2)
Includes
- Histoplasma Mycelia Antibodies by CF
- Histoplasma Yeast Antibodies by CF
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Label specimens plainly as 'acute' and 'convalescent.' |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.4 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
Days Performed
Sun - Sat
Turnaround Time
3 - 6 days
Methodology
| Name | Description |
|---|---|
| Semi-Quantitative Complement Fixation |
Special Info
Contaminated, hemolyzed or severely lipemic specimens will be rejected. This test is New York DOH approved.
Clinical Info
A titer of 1:8 or greater is generally considered presumptive evidence of histoplasmosis. A titer of 1:32 or greater or rising titers indicate strong presumptive evidence of histoplasmosis. Cross-reactions, usually at lower titers, may occur with other fungal disease. This complement fixation test detects total antibodies to mycelial and yeast antigens of Histoplasma.