Herpesvirus 7 PCR, Quant, CSF
Test Mnemonic
HV7QNT
CPT Codes
- 87799 - QTY (1)
LOINC ®
49399-9
Performing Laboratory
ViraCor-IBT Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Cerebrospinal fluid (CSF) | Sterile container | Frozen | Freeze immediately. Deliver to Cleveland Clinic Laboratories within 24 hours of collection. Specimen must be received by 12:00 noon EST on Fridays. Ship on dry ice. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | Unacceptable |
| Ambient | Unacceptable |
| Frozen | 96 hours |
Days Performed
Mon - Sat
Turnaround Time
2 - 3 days
Methodology
| Name | Description |
|---|---|
| Polymerase Chain Reaction (PCR) |
Reference Range
Special Info
Deliver to Cleveland Clinic Laboratories within 24 hours of collection. Specimen must be received by 12:00 noon EST on Fridays. Ship on dry ice.
Clinical Info
Assay range: 112 copies/mL to 1 x 10(8) copies/mL. HHV-7 is detectable in a variety of transplant settings, both HSCT and solid organ. Direct effects of HHV-7 include fever, rash, myelosuppression, encephalitis, and pneumonitis. Potentially more important are the indirect effects HHV-7 has on CMV disease, invasive fungal disease, and allograft dysfunction. Quantitative HHV-7 DNA PCR can be used to document the presence of the virus as well as track the course of infection. The primers and probes used in this assay are specific for known strains of HHV-7 based on similarity search algorithms. Additionally, no cross reactivity was detected when tested against adenoviruses, BKV, CMV, EBV, HSV-1, HSV-2, HHV-6 variant A, HHV-6 variant B, HHV-8, JCV, parvovirus B19, SV-40, and VZV.