Hematologic Neoplasm Fusion NGS Panel, Bone Marrow.
Test Mnemonic
HFMNGS
CPT Codes
- 81455 - QTY (1)
Aliases
- HemeFusion
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Aspirate, bone marrow | EDTA (Lavender) | Ambient | Refrigerated | Refrigerate ASAP |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | Stored up to 3 days. If testing is to be delayed, pending triage, store as NUCBUF |
| Ambient | If specimen is to be stored longer than 24 hours, it should be placed at 2-8 C for up to 3 days. If testing is to be delayed, pending triage, store as NUCBUF |
| Frozen | UNACCEPTABLE |
Days Performed
Mon - Fri
Turnaround Time
10 days
Methodology
| Name | Description |
|---|---|
| Next Gen Sequencing |
Special Info
ABL1, ABL2, AFDN (MLLT4), ALK, BCL11B, BCL2, BCL3, BCL6, BCR, BIRC3, BLNK, CBFB, CBL, CCND1, CCND2, CCND3, CD274, CD28, CDK6, CDKN2A, CEBPA, CEBPD, CEBPE, CEBPG, CHD1, CHIC2, CIITA, CREBBP, CRLF2, CSF1R, CTLA4, DEK, DGKH, DUSP22, EBF1, EIF4A1, EPOR, ERG, ETV6, FGFR1, FLT3, FOXP1, GLIS2, HLF, ID4, IKZF1, IKZF2, IKZF3, IL2RB, IRF4, IRF8, ITK, JAK2, KAT6A, KLF2, KMT2A, LMO1, LMO2, LYN, MALT1, MECOM, MEF2D, MLF1, MLLT10, MRTFA (MKL1), MUC1, MYC, MYH11, NF1, NFKB2, NOTCH1, NTRK3, NUP214, NUP98, NUTM1, P2RY8, PAG1, PAX5, PBX1, PDCD1, PDCD1LG2, PDGFRA, PDGFRB, PICALM, PML, PRDM16, PTK2B, RARA, RBM15, ROS1, RUNX1, RUNX1T1, SEMA6A, SETD2, STIL, SYK, TAL1, TCF3, TFG, TLX1, TLX3, TP63, TSLP, TYK2, VAV1, ZCCHC7, ZNF384.
Clinical Info
Detects common fusions in hematologic malignancies. Content is identical to the fusion component genes in the Acute Leukemia NGS panel.