Glutathione Total
Test Mnemonic
GLUTAT
CPT Codes
- 82978 - QTY (1)
LOINC ®
2383-8
Includes
- Glutathione Total
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 10 mL | Whole blood | ACD B (Yellow) | Place specimen on ice after draw. | Refrigerated | Critical Refrigerated. Transport whole blood in original collection container. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 8.5 mL | Whole blood | ACD A (Yellow) | Place specimen on ice after draw. | Refrigerated | Critical Refrigerated. Transport whole blood in original collection container. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 8.5 mL | ACD solution B | ||||
| 6.5 mL | ACD solution A |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Refrigerated | 3 weeks |
| Frozen | Unacceptable |
Days Performed
Varies
Turnaround Time
6 - 10 days
Methodology
| Name | Description |
|---|---|
| Quantitative, Kinetic |
Reference Range
Special Info
Hemolyzed specimens will be rejected. This test is New York state approved.
Clinical Info
Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia. Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by the performing laboratory. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.