FISH for MYC (8q24) Bone Marrow
Test Mnemonic
MYCFSM
CPT Codes
- 88271 - QTY (2)
- 88275 - QTY (1)
- 88291 - QTY (1)
- 88237 - QTY (1)
Includes
- FISH for MYC (8q24)
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 - 3 mL | Bone marrow | EDTA (Lavender) | Ambient | Ambient |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 - 3 mL | Bone marrow | Sodium heparin (Green) | Ambient | Ambient |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 48 hours |
| Refrigerated | Acceptable |
| Frozen | Not acceptable |
Days Performed
5 days per week
Turnaround Time
3 - 5 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Special Info
Specimens submitted for MYC amplification should not use this test code.
Clinical Info
This assay uses a dual color, break-apart probe to detect translocations involving the MYC gene. MYC translocations are seen in a wide variety of malignant lymphomas including Burkitt lymphoma, diffuse large B-cell lymphoma, and others. If no cells are available for analysis, no analysis charges will be incurred.