FISH for FUS (16p11.2)
Test Mnemonic
FUS
CPT Codes
- 88377 - QTY (1)
Aliases
- Flourescence In Situ Hybridization for FUS (16p11)
- FISH for FUS gene (16p11.2)
Includes
- LSI 16p11
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 slides | Slide (s), unstained | Clean container | Ambient | Ambient | One formalin-fixed, paraffin embedded block containing representative tissue OR unstained 4 μm tissue sections on electrostatically charged slides containing representative tumor. Tissue must be fixed in formalin NOT B5 or PREFER fixative |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Sample is formalin fixed and must not be fixed in Prefer or B5. |
Days Performed
5 days per week
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Clinical Info
Interphase FISH analysis utilizing a dual color, break-apart probe for the FUS gene 16p11.2. Rearrangements of the FUS gene are observed in low-grade fibromyxoid sarcoma. The translocation partner gene cannot be identified in this assay. If no cells are available for analysis, no analysis charges will be incurred.