Factor II Assay
Test Mnemonic
FIIC
CPT Codes
- 85210 - QTY (1)
LOINC ®
3289-6
Aliases
- Prothrombin Assay
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | Sodium citrate (Lt. Blue) | Frozen | Indicate previous prothrombin and partial thromboplastin time results on requisition. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 4 hours |
| Refrigerated | Unacceptable |
| Frozen | 14 days at -20 C; 6 months at -70 C |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Clotting Assay |
Reference Range
| Factor II Assay | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Days | 1 Days | Normal | 29 - 72 | % | 2 Days | 5 Days | Normal | 36 - 96 | % | 6 Days | 30 Days | Normal | 37 - 106 | % | 1 Months | 3 Months | Normal | 50 - 109 | % | 4 Months | 11 Months | Normal | 66 - 120 | % | 1 Years | 5 Years | Normal | 78 - 120 | % | 6 Years | 10 Years | Normal | 74-111 | % | 11 Years | 16 Years | Normal | 67-108 | % | 17 Years | 99 Years | Normal | 77-151 | % | Years | 99 Years | Urgent | After Pathologist Review: < 5 | % |
Special Info
This test does not detect the prothrombin G20210A polymorphism. For that assay order Prothrombin Gene Mutation. 3.2% sodium citrate is the preferred anticoagulant recommended by CLSI.
Clinical Info
Detecting coagulation deficiency of factor II. Factor II deficiency may be seen in congenital Factor II deficiency, in liver disease, vitamin K deficiency, coumadin therapy or DIC. Some patients with lupus anticoagulants may also have hypoprothrombinemia.