Dengue Virus IgG Antibody
Test Mnemonic
DENIGG
CPT Codes
- 86790 - QTY (1)
Includes
- Dengue Fever Virus Antibody, IgG
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. Parallel testing is preferred and convalescent specimens MUST be received within 30 days from receipt of the acute specimens. Label specimens plainly as 'acute' or 'convalescent.' |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. Parallel testing is preferred and convalescent specimens MUST be received within 30 days from receipt of the acute specimens. Label specimens plainly as 'acute' or 'convalescent.' |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
Days Performed
Mon, Wed, Fri
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Semi Quantitative Enzyme Linked Immunosorbent Assay |
Reference Range
| Dengue Virus IgG Antibody | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody. | 1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful. | 2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection. |
Special Info
Parallel testing is preferred and convalescent specimens MUST be received within 30 days from receipt of the acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens will be rejected. This test is New York DOH approved.
Clinical Info
Patients in the early stage of dengue fever virus infection may not have detectable IgG antibodies, as the IgG response may take several weeks to develop. In the absence of detectable IgG, testing for IgM class antibody is strongly recommended. The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.