Clonazepam
Test Mnemonic
CLONAS
CPT Codes
- 80346 - QTY (1)
- G0480 - QTY (1)
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | Potassium oxalate/sodium fluoride (Gray) | Refrigerated | Do not draw gel separator tube. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate plasma from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Refrigerated | Do not draw gel separator tube. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. | |
| 2 mL | Plasma | Sodium heparin (Green) | Refrigerated | Do not draw gel separator tube. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate plasma from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. | |
| 2 mL | Plasma | EDTA (Lavender) | Refrigerated | Do not draw gel separator tube. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate plasma from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | After separation from cells: 2 weeks |
| Ambient | After separation from cells: 1 week |
| Frozen | After separation from cells: 3 years (Avoid repeated freeze/thaw cycles) |
Days Performed
Tue, Fri
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Quantitative Liquid Chromatography - Tandem Mass Spectrometry |
Special Info
Patient Prep: Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Gel separator tubes are unacceptable. Plasma or whole blood collected in light blue (sodium citrate) tubes will be rejected. Hemolyzed specimens will be rejected. This test is New York DOH approved.
Clinical Info
Used to optimize drug therapy and monitor patient adherence. Adverse effects may include drowsiness, headache, fatigue and ataxia.