CK Isoenzymes




Test Mnemonic

CKISO

CPT Codes

  • 82550 - QTY (1)
  • 82552 - QTY (1)

Aliases

  • Creatine Kinase Isoenzymes

Includes

  • % CKMB
  • % CKMM
  • % CKBB
  • Creatine Kinase, Total

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) FrozenTransfer 1 mL serum to standard aliquot tube and freeze.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumNo additive (Red) FrozenTransfer 1 mL serum to standard aliquot tube and freeze.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
FrozenAfter separation from cells: 1 month (Avoid repeated freeze/thaw cycles)
RefrigeratedAfter separation from cells: 1 week
AmbientAfter separation from cells: Unacceptable

Days Performed

Sun - Sat

Turnaround Time

3 - 4 days

Methodology

Name Description
Electrophoresis 
Enzymatic 

Reference Range

% CKMB
Sex Age From Age To Type Range Range Unit
       Normal0 - 4%
% CKMM
Sex Age From Age To Type Range Range Unit
       Normal96 - 100%
Creatine Kinase
Sex Age From Age To Type Range Range Unit
Male  Days30 DaysNormal108 - 564U/L
Male6 Months35 MonthsNormal50 - 272U/L
Male3 Years6 YearsNormal56 - 281U/L
Male7 Years17 YearsNormal60 - 393U/L
       Male: 31 Days to 5 Months: 72 - 367 U/L 
       Male: 18 Years and older: 39 - 308 U/L 
       Female: 31 Days to 5 Months: 72 - 367 U/L 
       Female: 18 Years and older: 26 - 192 U/L 
Female  Days30 DaysNormal108 - 564U/L
Female6 Months35 MonthsNormal38 - 261U/L
Female3 Years6 YearsNormal40 - 222U/L
Female7 Years17 YearsNormal46 - 250U/L

Special Info

This test will detect CK macroenzymes. Specimens preserved in citrate, EDTA, fluoride, heparin, or iodoacetate are unacceptable. Grossly hemolyzed specimens will be rejected. This test is New York DOH approved.

Clinical Info

Aids in determining the etiology of elevated total creatine kinase.