Beta-2-Glycoprotein IgG and IgM
Test Mnemonic
B2GPGM
CPT Codes
- 86146 - QTY (2)
Aliases
- Beta-2-GPI
Includes
- Beta-2-GPI IgG
- Beta-2-GPI IgM
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | SST (Gold) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 day |
| Refrigerated | 7 days |
| Frozen | 1 year, up to 2 freeze thaw cycles |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Reference Range
| Beta-2 Glycoprotein, IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Negative: < 20 | SGU | Years | 99 Years | Normal | Low Positive: 20 - 80 | SGU | Years | 99 Years | Normal | High Positive: > 80 | SGU |
| Beta-2 Glycoprotein, IgM | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Negative: < 20 | SMU | Years | 99 Years | Normal | Low Positive: 20 - 80 | SMU | Years | 99 Years | Normal | High Positive: > 80 | SMU |
Clinical Info
Beta-2 GP autoantibodies are found in patients with antiphospholipid syndrome (APS) and are associated with increased risk of venous and arterial thrombosis and thrombocytopenia. Beta-2 GP autoantibodies are found only in patients with autoimmune diseases, while cardiolipin autoantibodies can be transiently found in infectious disease.