Anaplasma phagocytophilum (HGA) Antibodies, IgG and IgM
Test Mnemonic
ANIGM
CPT Codes
- 86666 - QTY (2)
Aliases
- HGE
- Phagocytophilum Titer
Includes
- Anaplasma phagocytophilum (HGA) Ab, IgG
- Anaplasma phagocytophilum (HGA) Ab, IgM
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. For parallel testing, convalescent specimens must be received within 30 days from receipt of the acute specimens. Label specimens plainly as 'acute' and 'convalescent.' |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.4 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year |
Days Performed
Tue, Fri
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Indirect Fluorescent Antibody (IFA) |
Reference Range
| HGA Ab, IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:80 - No significant level of IgG antibodies to A. phagocyophilum detected. | > or = 1:80 - Suggestive of recent or past infection with A. phagocytophilum. | ||||
| HGA Ab, IgM | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:16 - No significant levels of IgM antibodies to A. phagocytophilum detected. | > or = 1:16 - Suggestive of current or recent infection with A. phagocytophilum. |
Special Info
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, turbid, or lipemic specimens will be rejected. This test is New York DOH approved.
Clinical Info
Acceptable test for acute or convalescent phase of infection from A. phagocytophilum. May be useful when PCR testing is not an option (e.g., outside the 2 week window for acute phase). However, PCR testing is generally preferred.