Alkaline Phosphatase, Bone Specific
Test Mnemonic
APBONE
CPT Codes
- 84080 - QTY (1)
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | SST (Gold) | N/A | Frozen, Critical | Critical frozen. Remove serum from cells ASAP, transfer to standard aliquot tube and freeze. Separate specimens must be submitted when multiple tests are ordered. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Plasma | Sodium or Lithium heparin (Green) | N/A | Frozen, Critical | Critical frozen. Remove plasma from cells ASAP, transfer to standard aliquot tube and freeze. Separate specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 hours |
| Refrigerated | After separation from cells: 2 days |
| Frozen | After separation from cells: 2 months |
Days Performed
Sun - Sat
Turnaround Time
2 - 3 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescence Immunoassay (CLIA) |
Reference Range
| Alkaline Phosphatase, Bone Specific | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Male | 6 Months | 24 Months | Normal | 31.6 - 122.6 | ug/L | Male | 3 Years | 6 Years | Normal | 31.3 - 103.4 | ug/L | Male | 7 Years | 9 Years | Normal | 48.6 - 140.4 | ug/L | Male | 10 Years | 12 Years | Normal | 48.8 - 155.5 | ug/L | Male | 13 Years | 15 Years | Normal | 27.8 - 210.9 | ug/L | Male | 16 Years | 17 Years | Normal | 15.3 - 126.8 | ug/L | Male | 18 Years | 24 Years | Normal | 10.0 - 28.8 | ug/L | Male | 25 Years | 99 Years | Normal | 6.5 - 20.1 | ug/L | Female | 6 Months | 24 Months | Normal | 33.4 - 145.3 | ug/L | Female | 3 Years | 6 Years | Normal | 32.9 - 108.6 | ug/L | Female | 7 Years | 9 Years | Normal | 36.3 - 159.4 | ug/L | Female | 10 Years | 12 Years | Normal | 44.2 - 163.3 | ug/L | Female | 13 Years | 15 Years | Normal | 14.8 - 136.2 | ug/L | Female | 16 Years | 17 Years | Normal | 10.5 - 44.8 | ug/L | Female: Premenopausal: 4.5 - 16.9 ug/L | Female: Postmenopausal: 7.0 - 22.4 ug/L |
Special Info
Critical frozen. Grossly hemolyzed specimens will be rejected. Urine is unacceptable. This test is New York DOH approved.
Clinical Info
Liver alkaline phosphatase can affect the measurement of bone specific alkaline phosphatase in this assay. Each 100 U/L of liver alkaline phosphatase contributes an additional 2.5 to 5.8 ug/L to the bone specific alkaline phosphatase result.