5-Methyltetrahydrofolate
Test Mnemonic
5MTH
CPT Codes
- 82542 - QTY (1)
Performing Laboratory
Medical Neurogenetics
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4.5 mL | Cerebrospinal fluid (CSF) | Set of 5 MNG Collection Tubes | Frozen | CSF should be collected from the first drop into the containers in the order indicated. Fill each tube to the marked line (0.5 mL in tube 1; 1.0 mL in tubes 2, 3, 4, and 5). Place specimens on ice after collection. If specimen is blood contaminated, the tubes should immediately be centrifuged (prior to freezing) and the clear CSF transferred to new similarly labeled tubes then frozen ASAP at -80 C. Call Client Services at 800-628-6216 to obtain appropriate specimen collection containers. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Cerebrospinal fluid (CSF) | Clean container | Frozen | This specimen to be used if 5-MTH is the only CSF Medical Neurogenetics test ordered. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Frozen | Indefinitely |
| Refrigerated | Unacceptable |
Days Performed
Tue - Fri
Turnaround Time
15 - 17 days
Methodology
| Name | Description |
|---|---|
| High Performance Liquid Chromatography with Electrochemical Detection |
Reference Range
| 5-Methyltetrahydrofolate | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Months | 6 Months | Normal | 40 - 240 | nmol/L | 6 Months | 24 Months | Normal | 40 - 187 | nmol/L | 2 Years | 5 Years | Normal | 40 - 150 | nmol/L | 5 Years | 10 Years | Normal | 40 - 128 | nmol/L | 10 Years | 99 Years | Normal | 40 - 120 | nmol/L |
Special Info
Prior to collecting sample, contact Client Services to obtain sample collection containers consisting of 5 numbered tubes per set. CSF should be collected from the first drop into the containers in the order indicated. Fill each tube to the marked line (0.5 mL in tube 1; 1.0 mL in tubes 2, 3, 4, and 5). Tube #3 contains antioxidants to protect the sample from oxidation. One set of vials is required per patient.
Clinical Info
Cerebral Folate deficiency