5‐HIAA, Plasma




Test Mnemonic

5HIAAD

CPT Codes

  • 83497 - QTY (1)

Includes

  • 5-HIAA, Plasma

Performing Laboratory

LabCorp

FDA Category

Laboratory Developed Test


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLPlasmaSodium heparin (Green) FrozenSeparate plasma from cells within 45 minutes of collection and freeze aliquot. Patient should avoid bananas, avocados, plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for at least 72 hours prior to collection. Separate specimens must be submitted when multiple tests are ordered.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLPlasmaEDTA (Lavender) FrozenSeparate plasma from cells within 45 minutes of collection and freeze aliquot. Patient should avoid bananas, avocados, plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for at least 72 hours prior to collection. Separate specimens must be submitted when multiple tests are ordered.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
FrozenAfter separation from cells: 14 days (6 freeze/thaw cycles)
RefrigeratedAfter separation from cells: 3 days
AmbientAfter separation from cells: 3 days

Days Performed

Varies

Turnaround Time

9 - 16 days

Methodology

Name Description
High-Pressure Liquid Chromatography (HPLC)/Tandem Mass Spectrometry 

Reference Range

5-HIAA, Plasma
Sex Age From Age To Type Range Range Unit
       < 22 ng/mL 

Special Info

Separate plasma from cells within 45 minutes of collection and freeze aliquot. Patient should avoid bananas, avocados, plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for at least 72 hours prior to collection. Separate specimens must be submitted when multiple tests are ordered. Grossly hemolyzed specimens will be rejected.

Clinical Info

Plasma 5-hydroxy-indoleacetic acid (5HIAA or 5-HIAA) is a metabolite of serotonin that can be elevated as a result of carcinoid tumors/carcinoid syndrome.