April 2021: Changes to AIDYSA, ENCSER, PARNEO, LAMBRT, & MYGRAV Panels

Special Communication

Changes to AIDYSA, ENCSER, PARNEO, LAMBRT, & MYGRAV Panels

Changes to Reference Ranges

Effective May 11, 2021.

These changes will affect interfaced clients.

Autoimmune Dysautonomia Evaluation, Serum (AIDYSA)

Remove:
• (MUSBND) ACh Receptor (Muscle) Binding Ab
• (PARGAD) GAD65 Ab Assay
• (VGKC) Neuronal (V-G) K+ Channel Ab
• N-Type Calcium Channel Ab
• P/Q-Type Calcium Channel Ab
• Striational (Striated Muscle) Ab
• Reflex (MUSMOD) Muscle modulating antibody
• Reflex (CASRFX) CASPR2-IgG CBA
• Reflex (CRMPSX) CRMP-5-IgG
• Reflex (LG1RFX) LGI1-IgG CBA
• Reflex (PURK2X) Purkinje Cell Cytoplasmic Ab Type 2

Add to Panel:
• (CASRFX) CASPR2-IgG CBA
• (CRMPSX) CRMP-5-IgG
• (LG1RFX) LGI1-IgG CBA
• (PURK2X) Purkinje Cell Cytoplasmic Ab Type 2

Autoimmune Encephalopathy Evaluation, Serum (ENCSER)

Remove:
• (GANG3) AChR Ganglionic Neuronal Ab, S
• N-Type Calcium Channel Ab
• P/Q-Type Calcium Channel Ab
• Reflex (MUSMOD) Muscle modulating antibody

Paraneoplastic Autoantibody Evaluation, Serum (PARNEO)

Remove:
• Striational (Striated Muscle) Ab
• N-Type Calcium Channel Ab
• Reflex (MUSMOD) Muscle modulating antibody

Add:
• Reflex (ACMFCS) AChR Modulating Flow Cytometry, S

Test Discontinuations

Effective May 11, 2021.

Myasthenia Gravis/Lambert-Eaton Syndrome (LAMBRT)

Reason:
Discontinued by reference lab (Mayo Clinic Laboratories)

Alternative Test:
Myasthenia Gravis (MG)/Lambert-Eaton Syndrome (LES) Evaluation, Serum (MGLESE)

Myasthenia Gravis Evaluation, Adult (MYGRAV)

Reason:
Discontinued by reference lab (Mayo Clinic Laboratories)

Alternative Test:
Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum (MYSGRV)