Special Communication
May 2019: Upcoming Test Changes, Updates, and Discontinuations
Changes to Reference Ranges
Effective April 24, 2019.
Changes to Specimen Requirements
Effective May 20, 2019.
Drug Detection Panel, TOF-MS, Umbilical Cord Tissue (DRGTOF)
Volume:
8 inches of umbilical cord (approximately the width of a sheet of paper)
Minimum Volume:
6 inches
Collection Instructions:
Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or water. Pat the cord dry and transport the specimen in a routine urine collection cup or use a Security Kit for Meconium/Umbilical Drug Detection.
Transport Temperature:
Refrigerated
Reference Range:
Gabapentin: Cut-off 10 ng/g
Buprenorphine-G will be removed; all other reference ranges will remain the same.
Drug Detection Panel, Umbilical Cord Tissue, with Marijuana Metabolite (DTOFMP)
Volume:
8 inches of umbilical cord (approximately the width of a sheet of paper)
Minimum Volume:
8 inches
Collection Instructions:
Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or water. Pat the cord dry and transport the specimen in a routine urine collection cup or use a Security Kit for Meconium/Umbilical Drug Detection.
Transport Temperature:
Refrigerated
Reference Range:
Gabapentin: Cut-off 10 ng/g
Buprenorphine-G will be removed; all other reference ranges will remain the same.
Marijuana Metabolite, Umbilical Cord Tissue, Qualitative (DRGTHC)
Volume:
8 inches of umbilical cord (approximately the width of a sheet of paper)
Minimum Volume:
6 inches
Collection Instructions:
Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or water. Pat the cord dry and transport the specimen in a routine urine collection cup or use a Security Kit for Meconium/Umbilical Drug Detection.
Transport Temperature:
Refrigerated
Test Build Changes
These updates may require changes to the Test Build for interfaced clients.
Effective May 20, 2019.
Discontinued Tests
Effective May 20, 2019.
5-Fluorouracil Toxicity, Chemo Response, 5 Mut (5FLUO)
We suggest ordering Dihydropyrimidine Dehydrogenase (DPYD), 3 Variants (5FUDPD).
Cytochrome P450 2D6 (CYP2D6) Geno (2D6GEN)
We suggest ordering the new test, CYP2D6 (Cytochrome P450 2D6) (2D6GTP).
Cyto P450 2C19 – 9 Variants (2C19PL)
We suggest ordering the new test, CYP2C19 (Cytochrome P450 2C19) (2C19CY).
Warfarin Sensitivity Genotyping (WARSEN)
We suggest ordering new test Warfarin Sensitivity (CYP2C8, CYP2C9, CYP4F2, VKORC1) Genotyping (WRFSEN).
Fats, Urine (UFAT)
Changes to Specimen Requirements
Effective May 29, 2019.
Complement Deficiency Assay (COMPD)
Volume:
1 mL, serum
Minimum Volume:
0.25 mL
Collection Container:
Red (Serum) No Additive Tube
Collection Instructions:
Allow sample to clot, then separate serum from cells as soon as possible. Centrifuge, then remove serum and freeze at minus 20°C or colder (up to 7 days post-draw). Minus 70 °C or colder is preferred and is acceptable up to 30 days post-draw.
Transport Temperature:
Frozen
Test Build Changes
Effective June 24, 2019.
These updates may require changes to the Test Build for interfaced clients.
HIV-1 Integrase Genotype (HIVIGT)
Any additional information will be included in a future Technical Update. If you have any questions about these changes, please contact Client Services for assistance.