Aripiprazole and Metabolite
Test Mnemonic
ARPRZL
CPT Codes
- 80342/G0480 - QTY (1)
Aliases
- Abilify
Includes
- Aripiprazole Serum/Plasma
- Dehydroaripiprazole, Serum/Plasma
- Total Aripiprazole and Metabolite S/P
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | EDTA (Lavender) | Refrigerated | Separate plasma from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 2 weeks |
| Frozen | 2 weeks |
| Ambient | 2 weeks |
Days Performed
Wed, Sat
Turnaround Time
2 - 9 days
Methodology
| Name | Description |
|---|---|
| Quantitative Liquid Chromatography - Tandem Mass Spectrometry |
Reference Range
| Total Aripiprazole and Metabolite | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Therapeutic: 150.0 - 500.0 | ng/mL | Normal | Toxic: >/= 1000.0 | ng/mL |
Special Info
Gel separator tubes will be rejected. This test is New York state approved.
Clinical Info
This test is useful to optimize drug therapy and monitor patient adherence. The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Adverse effects to aripiprazole therapy may include headache, nausea, somnolence and blurred vision.