Plasma Carnitine Free/Total and Acylcarnitines Panel
Test Mnemonic
PCAPNL
CPT Codes
- 82379 - QTY (1)
- 82017 - QTY (1)
Includes
- Carnitine Total
- Carnitine Free (FC)
- Acylcarnitine (AC)
- AC/FC Ratio
- Interpretation
- Acetylcarnitine, C2
- Acrylylcarnitine, C3:1
- Propionylcarnitine, C3
- Formiminoglutamate, FIGLU
- Iso-/Butyrylcarnitine, C4
- Tiglylcarnitine, C5:1
- Isovaleryl-/2-Methylbutyrylcarn C5
- 3-OH-iso-/butyrylcarnitine, C4-OH
- Hexenoylcarnitine, C6:1
- Hexanoylcarnitine, C6
- 3-OH-isovalerylcarnitine, C5-OH
- Benzoylcarnitine
- Heptanoylcarnitine, C7
- 3-OH-hexanoylcarnitine, C6-OH
- Phenylacetylcarnitine
- Salicylcarnitine
- Octenoylcarnitine, C8:1
- Octanoylcarnitine, C8
- Malonylcarnitine, C3-DC
- Decadienoylcarnitine, C10:2
- Decenoylcarnitine, C10:1
- Decanoylcarnitine, C10
- Methylmalonyl-/succinylcarn, C4-DC
- 3-OH-decenoylcarnitine, C10:1-OH
- Glutarylcarnitine, C5-DC
- Dodecenoylcarnitine, C12:1
- Dodecanoylcarnitine, C12
- 3-Methylglutarylcarnitine, C6-DC
- 3-OH-dodecenoylcarnitine, C12:1-OH
- 3-OH-dodecanoylcarnitine, C12-OH
- Tetradecadienoylcarnitine, C14:2
- Tetradecenoylcarnitine, C14:1
- Tetradecanoylcarnitine, C14
- Octanedioylcarnitine, C8-DC
- 3-OH-tetradecenoylcarnitine C14:1OH
- 3-OH-tetradecanoylcarnitine, C14-OH
- Hexadecenoylcarnitine, C16:1
- Hexadecanoylcarnitine, C16
- 3-OH-hexadecenoylcarnitine,C16:1-OH
- 3-OH-hexadecanoylcarnitine, C16-OH
- Octadecadienoylcarnitine, C18:2
- Octadecenoylcarnitine, C18:1
- Octadecanoylcarnitine, C18
- Dodecanedioylcarnitine, C12-DC
- 3-OH-octadecadienoylcarn, C18:2-OH
- 3-OH-octadecenoylcarnitine C18:1-OH
- 3-OH-octadecanoylcarnitine, C18-OH
- Comment (ACRN)
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Plasma | Sodium heparin (Green) | Frozen | Multiple specimen tubes must be collected for this panel. This tube is for test: Carnitine Free and Total, Plasma (CARNFT). Collect specimen just prior to a scheduled meal or feeding. Patient age is required. Centrifuge and aliquot plasma into standard aliquot tube. | |
| 0.1 mL | Plasma | Sodium heparin (Green) | Frozen | Multiple specimen tubes must be collected for this panel. This tube is for test: Acylcarnitines, Quantitative, Plasma (ACRNPL). Collect specimen just prior to a scheduled meal or feeding. Patient age is required. Centrifuge and aliquot plasma into standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Variable | The aliquot for Carnitine Free and Total, Plasma (CARNFT) must have a minimum volume of 0.2 mL. The aliquot for Acylcarnitines, Quantitative, Plasma (ACRNPL) must have a minimum of 0.04 mL. |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | 60 days |
| Refrigerated | 21 days |
| Ambient | 7 days |
Days Performed
Mon - Fri
Turnaround Time
3 - 6 days
Methodology
| Name | Description |
|---|---|
| Flow Injection Analysis-Tandem Mass Spectrometry (FIA-MS/MS) |
Special Info
This test is New York State approved.
Clinical Info
This test is useful for evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias, fatty acid oxidation disorders, and primary carnitine deficiency using plasma specimens. It is also useful for diagnosis of fatty acid oxidation disorders and several organic acidurias using plasma specimens. It is also useful in evaluating treatment during follow-up of patients with fatty acid beta-oxidation disorders and several organic acidurias.