Asparaginase Enzyme Activity
Test Mnemonic
ASNASE
CPT Codes
- 82657 - QTY (1)
Aliases
- Erwinaze
- Oncaspar
- Pegaspargase
Includes
- Asparaginase Activity
Performing Laboratory
NEXT Molecular Analytics
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Record time and date of most recent asparaginase administration. Immediately after collection, invert tube gently five times then allow specimen to clot for 30 to 60 minutes. Centrifuge, then use a disposable pipette to transfer 1 mL serum to standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Record time and date of most recent asparaginase administration. Allow specimen to clot for 30 to 60 minutes. Centrifuge, then use a disposable pipette to transfer 1 mL serum to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 14 days |
| Frozen | 3 years |
| Ambient | 7 days |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Coupled enzymatic assay |
Special Info
Shipping kits with sample submission forms are stored in Main Campus Send Outs laboratory. Record the sample date and time of collection on the sample submission form as well as the time and date of the most recent asparaginase administration.
Clinical Info
Lower limit of quantitation is 0.013 IU/mL. This test is useful in determining asparaginase activity present during treatment and identifying patients with hypersensitivity to asparaginase.