FISH for Chronic Lymphocytic Leukemia, Bone Marrow
Test Mnemonic
CLLFSM
CPT Codes
- 88271 - QTY (7)
- 88275 - QTY (3)
- 88291 - QTY (1)
- 88237 - QTY (1)
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 - 3 mL | Bone marrow | Sodium heparin (Green) | Ambient | Ambient | |
| 2 - 3 mL | Bone marrow | EDTA (Lavender) | Ambient | Ambient |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 48 hours, preferred |
| Refrigerated | 48 hours, Not preferred but acceptable |
| Frozen | Not acceptable |
Days Performed
5 days per week
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Special Info
This test currently includes FISH testing for 17p(TP53), 11q(ATM), 12 centromere and 13q(D13S319,LAMP1). IgH/CCND1 is being added to this panel
Clinical Info
Prognostic indicator for patients with CLL (Chronic Lymphocytic Leukemia).