Hematologic Neoplasm Fusion NGS Panel, Other.
Test Mnemonic
HFONGS
CPT Codes
- 81455 - QTY (1)
Aliases
- HemeFusion
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Ten | Slide(s), unstained & unbaked | Slides, unstained | Ambient | Ambient | Need 10 charged, unbaked, unstained slides or 10 x 7 micron curls (scrolls) plus 1 H&E slide with best tumor area circled containing at least 8% tumor |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | FFPE tissue and clot section slides and curls are transported and stored at ambient temperature or refrigerated indefinitely |
| Refrigerated | FFPE tissue and clot section slides and curls are transported and stored at ambient temperature or refrigerated indefinitely |
| Frozen | UNACCEPTABLE |
Days Performed
Mon - Fri
Turnaround Time
10 days
Methodology
| Name | Description |
|---|---|
| Next Gen Sequencing |
Special Info
ABL1, ABL2, AFDN (MLLT4), ALK, BCL11B, BCL2, BCL3, BCL6, BCR, BIRC3, BLNK, CBFB, CBL, CCND1, CCND2, CCND3, CD274, CD28, CDK6, CDKN2A, CEBPA, CEBPD, CEBPE, CEBPG, CHD1, CHIC2, CIITA, CREBBP, CRLF2, CSF1R, CTLA4, DEK, DGKH, DUSP22, EBF1, EIF4A1, EPOR, ERG, ETV6, FGFR1, FLT3, FOXP1, GLIS2, HLF, ID4, IKZF1, IKZF2, IKZF3, IL2RB, IRF4, IRF8, ITK, JAK2, KAT6A, KLF2, KMT2A, LMO1, LMO2, LYN, MALT1, MECOM, MEF2D, MLF1, MLLT10, MRTFA (MKL1), MUC1, MYC, MYH11, NF1, NFKB2, NOTCH1, NTRK3, NUP214, NUP98, NUTM1, P2RY8, PAG1, PAX5, PBX1, PDCD1, PDCD1LG2, PDGFRA, PDGFRB, PICALM, PML, PRDM16, PTK2B, RARA, RBM15, ROS1, RUNX1, RUNX1T1, SEMA6A, SETD2, STIL, SYK, TAL1, TCF3, TFG, TLX1, TLX3, TP63, TSLP, TYK2, VAV1, ZCCHC7, ZNF384.
Clinical Info
Detects common fusions in hematologic malignancies. Content is identical to the fusion component genes in the Acute Leukemia NGS panel.