Head and Neck Next Generation Sequencing
Test Mnemonic
HDNK
CPT Codes
- 81445 - QTY (1)
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 10 mm square | Block, Formalin fixed paraffin | Slides | Ambient | Formalin-fixed paraffin-embedded tissue slides. Transport and store slides at ambient temperature. 10 unstained sections FFPE tissue on charged, unbaked slides plus one H&E stained section with best tumor area circled by a pathologist. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Indefinitely for FFPET slides. FFPET slides are transported at ambient temperature. |
| Frozen | Not acceptable. |
| Refrigerated | Not acceptable. |
Days Performed
Once per week
Turnaround Time
14 days
Methodology
| Name | Description |
|---|---|
| Next Gen Sequencing |
Special Info
The following genes are interrogated: ALK, BRAF, CAMTA1, CRTC1, ETV6, EWSR1, FOS, FOSB. FOXO1, FUS, GLI1, HMGA2, MAML2, MKL2, MYB, NCOA1, NR4A3, NTRK1, NTRK2, NTRK3, NUTM1, PAX3, PAX7, PLAG1, PRKD1, RET, SS18, STAT6, TFE3, AND YAP1.