Anti-Nuclear Antibodies by IFA, Synovial Fluid
Test Mnemonic
BFANA
CPT Codes
- 86038 - QTY (1)
LOINC ®
14613-4
Aliases
- ANA Synovial Fluid
Includes
- ANA by IFA, Synovial Fluid
Performing Laboratory
LabCorp
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Fluid, synovial | Sterile container | Frozen |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL | Note: This volume does NOT allow for repeat testing. |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | 60 days (1 freeze/thaw cycle) |
| Refrigerated | 14 days |
| Ambient | 7 days |
Days Performed
Varies
Turnaround Time
6 - 8 days
Methodology
| Name | Description |
|---|---|
| Indirect Fluorescent Antibody (IFA) |
Reference Range
Special Info
This test reflexes to Synovial Fluid ANA Titer and Pattern if ANA by IFA is positive in order to rule out false positive ANA by IFA. Bacterial contamination, gross hemolysis, lipemic or icteric specimens, and specimens other than synovial fluid are unacceptable.
Clinical Info
Anti-nuclear antibodies (ANA) are commonly found in a variety of autoimmune diseases. Antibody frequency increases with age in apparently healthy people. ANA patterns on HEp-2 slides provide only general clues about particles (chromatin, nucleosomes, and spliceosomes). ANA patterns (other than centromere pattern) are not reliably correlated with the presence of specific antibodies and must be further evaluated by enzyme immunoassay using individual ENA antigens.