75 gram, fasting, 2-hour, non-gestational glucose tolerance




Test Mnemonic

GTNG2

CPT Codes

  • 82951 - QTY (1)

Includes

  • Fasting
  • 1 Hour
  • 2 Hour

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLPlasmaPotassium oxalate/sodium fluoride (Gray) Centrifuge and refrigerate.Aliquot into CCL aliquot tube

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.3 mL     

Stability

Environmental Condition Description
Ambient24 hours
RefrigeratedAfter removed from cells: 72 hours
FrozenUnacceptable

Days Performed

Sun - Sat

Turnaround Time

8 hours

Methodology

Name Description
Glucose Hexokinase 

Reference Range

1 Hour
Sex Age From Age To Type Range Range Unit
       NormalSee comment 
       Urgent>500mg/dL
       UrgentInpatient only: 40-49 mg/dL (First result only, once every 24 hours.)mg/dL
       Critical<40mg/dL
2 Hour
Sex Age From Age To Type Range Range Unit
       Normal74-139mg/dL
       Urgent>500mg/dL
       UrgentInpatient only: 40-49 mg/dL (First result only, once every 24 hours.)mg/dL
       Critical<40mg/dL
Fasting
Sex Age From Age To Type Range Range Unit
       Normal74 - 99mg/dL
       Urgent>500mg/dL
       UrgentInpatient only: 40-49 mg/dL (First result only, once every 24 hours.)mg/dL
       Critical<40mg/dL

Special Info

Patient should be fasting at least 8 hours prior to the test. Collect a fasting specimen. Then administer 75 grams of Dextrose within 5 minutes. Collect specimens at 1 and 2 hours post glucose load. Indicate collection time on each specimen.

Clinical Info

Confirmation of diabetes mellitus American Diabetes Association guidelines state a diabetes mellitus diagnosis is preliminarily made when the fasting plasma glucose meets or exceeds 126 mg/dL and/or the 2 hr glucose tolerance meets or exceeds 200 mg/dL. In the absence of unequivocal hyperglycemia, results should be confirmed with repeat testing. Patients are at increased risk for diabetes mellitus (prediabetes) when the fasting glucose is 100 to 125 mg/dL or the 2 hr glucose tolerance result is 140 to 199 mg/dL. A diagnostic cutoff for the 1 hr time point is not established, and should be clinically determined.

Technical Brief