Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF
Test Mnemonic
FANCSF
CPT Codes
- 86612 - QTY (1)
- 86606 - QTY (1)
- 86635 - QTY (1)
- 86698 - QTY (2)
Aliases
- FUNGAL ABs with Reflex,CS
- FUNGAL ABs with Rflx, CSF
Includes
- Coccidioides Ab by CF, CSF
- Histoplasma M, CSF (CF)
- Histoplasma Y, CSF (CF)
- Aspergillus Antibody, CSF (CF)
- Blastomyces Antibodies EIA, CSF
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Cerebrospinal fluid (CSF) | Clean container | Refrigerated | Transfer 1 mL CSF into standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 2 weeks |
| Frozen | 1 year (Avoid repeated freeze/thaw cycles) |
| Ambient | 48 hours |
Days Performed
Sun - Sat
Turnaround Time
3 - 7 days
Methodology
| Name | Description |
|---|---|
| Immunodiffusion (ID) | |
| Semi Quantitative Enzyme Linked Immunosorbent Assay | |
| Semi-Quantitative Complement Fixation |
Reference Range
| Aspergillus Ab CSF (CF) | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| <1:2 | |||||
| Blastomyces Ab EIA, CSF | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative: Less than or equal to 0.9 IV | Equivocal: 1.0 - 1.4 IV | Positive: Greater than or equal to 1.5 IV | |||
| Coccidioides Ab by CF, CSF | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| <1:2 | |||||
| Histoplasma Mycelia, CSF (CF) | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| <1:2 | |||||
| Histoplasma Yeast, CSF (CF) | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| <1:2 |
Special Info
If Blastomyces antibodies are equivocal or positive by immunoassay then Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF will be added at an additional charge. Body fluids other than cerebrospinal fluid (CSF) are not acceptable. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens are unacceptable.
Clinical Info
This test detects antibodies to Aspergillus, Coccidioides, and Histoplasma by complement fixation and Blastomyces by immunoassay. Negative fungal serology does not rule out the possibility of current infection.