Zinc, Urine Quantitative




Test Mnemonic

UZINCQ

CPT Codes

  • 84630 - QTY (1)

Aliases

  • 24 hour Urine Zinc
  • Normalized Urine Zinc
  • Random Urine Zinc
  • Urine Zinc Concentration
  • Zinc/Creatinine Ratio
  • Zn Urine

Includes

  • Hours Collected
  • Total Volume
  • Zinc, Urine - per volume
  • Zinc, Urine - per 24h
  • Creatinine, Urine - per volume
  • Creatinine, Urine - per 24h
  • Zinc, Urine - ratio to CRT

Performing Laboratory

ARUP

FDA Category

Laboratory Developed Test


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
8 mLUrine, 24-hour (well-mixed)Plastic containerRefrigerate during collection.RefrigeratedPatient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
8 mLUrine, randomPlastic container RefrigeratedPatient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Refrigerated2 weeks
Ambient1 week
Frozen1 year

Days Performed

Sun - Sat

Turnaround Time

2 - 6 days

Methodology

Name Description
Inductively Coupled Plasma / Mass Spectrometry (ICP-MS) 

Special Info

Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen. Urine transported in a non-trace element-free tube or contaminated with iodine, gadolinium, blood, fecal material or acid preservative will be rejected. This test is New York DOH approved.

Clinical Info

This test may be useful as an indicator of acute toxicity. Zinc is predominantly eliminated in the feces. Elevated urine zinc may suggest excessive zinc supplementation but should be interpreted with a corresponding serum or plasma zinc concentration.