FISH for SRY
Test Mnemonic
SRYFSH
CPT Codes
- 88273 - QTY (1)
- 88271 - QTY (2)
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Blood | Sodium heparin (Green) | Ambient | Ambient | For newborn and infant draws, a minimum of 0.5 mL whole blood is imposed. Unacceptable Conditions:Frozen specimens. Paraffin-embedded specimens. Clotted specimens. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Other tube and container types may be acceptable. Contact client services to inquire further. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 72 hours |
| Refrigerated | 72 hours |
| Frozen | Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Reference Range
Clinical Info
FISH for SRY (Sex-determining Region Y) identifies the presence or absence of the SRY locus by analyzing cells in interphase and/or metaphase with direct labeled FISH probes specific to the SRY gene on chromosome Y at band Yp11.3. The clinical utility of this test is multifaceted.