FISH for XY
Test Mnemonic
XYFSH
CPT Codes
- 88273 - QTY (1)
- 88271 - QTY (2)
Performing Laboratory
Cleveland Clinic Laboratories
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Sodium heparin (Green) | Ambient | Ambient | For newborn and infant draws, a minimum of 0.5ml whole blood is imposed. Unacceptable conditions: Frozen specimens, Paraffin-embedded specimens and clotted specimens. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Other tube and container types may be acceptable. Contact client services to inquire further. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 72 hours |
| Refrigerated | 72 hours |
| Frozen | Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Reference Range
| FISH XY Interpretation | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Refer to Report |
Clinical Info
FISH for the X and Y chromosomes identifies the sex chromosome constitution of individual nuclei in interphase and specific chromosome identity in cells in metaphase with direct labeled FISH probes specific to the X and Y chromosome centromeres.