Estradiol by Tandem Mass Spectrometry | Cleveland Clinic Laboratories

Estradiol by Tandem Mass Spectrometry Print

Test Mnemonic

ESTMS

CPT Codes

82670 - QTY (1)

Performing Laboratory

ARUP

FDA Category

Laboratory Developed Test

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.5 mL	Serum	SST (Gold)		Refrigerated	Separate serum or plasma from cells within 2 hours after collection.

Alternate Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.5 mL	Plasma	EDTA (Lavender)		Refrigerated	Separate serum or plasma from cells within 2 hours of collection.
0.5 mL	Plasma	Sodium or Lithium heparin (Green)		Refrigerated	Separate serum or plasma from cells within 2 hours of collection.

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.3 mL

Stability

Environmental Condition	Description
Ambient	After separation from cells: 48 hours
Frozen	After separation from cells: 1 month
Refrigerated	After separation from cells: 1 week

Days Performed

Sun - Sat

Turnaround Time

2 - 6 days

Methodology

Name	Description
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference Range

Estradiol
Sex	Age From	Age To	Type	Range	Range Unit
Female			Normal	Tanner Stage I: < 56.0	pg/mL
Female	18 Years	99 Years	Normal	Postmenopausal: 2.0 - 21.0	pg/mL
Female	18 Years	99 Years	Normal	Luteal Phase: 50.0 - 150.0	pg/mL
Female			Normal	Tanner Stage II: 2.0 - 133.0	pg/mL
Female	18 Years	99 Years	Normal	Late Follicular Phase: 100.0 - 400.0	pg/mL
Female	18 Years	99 Years	Normal	Early Follicular Phase: 30.0 - 100.0	pg/mL
Female	16 Years	17 Years	Normal	2.0 - 266.0	pg/mL
Female	13 Years	15 Years	Normal	9.0 - 249.0	pg/mL
Female	10 Years	12 Years	Normal	1.0 - 87.0	pg/mL
Female	7 Years	9 Years	Normal	< 36.0	pg/mL
Female			Normal	Tanner Stage IV and V: 2.0 - 259.0	pg/mL
Female			Normal	Tanner Stage III: 12.0 - 277.0	pg/mL
Male	16 Years	17 Years	Normal	3.0 - 34.0	pg/mL
Male	13 Years	15 Years	Normal	1.0 - 36.0	pg/mL
Male	10 Years	12 Years	Normal	< 11.0	pg/mL
Male	7 Years	9 Years	Normal	< 7.0	pg/mL
Male			Normal	Tanner Stage IV and V: 3.0 - 35.0	pg/mL
Male			Normal	Tanner Stage III: 1.0 - 35.0	pg/mL
Male			Normal	Tanner Stage II: < 10.0	pg/mL
Male			Normal	Tanner Stage I: < 8.0	pg/mL
Male	18 Years	99 Years	Normal	10.0 - 42.0	pg/mL

Special Info

Separate serum or plasma from cells within 2 hours of collection. This test is New York DOH approved.