Buprenorphine and Metabolites, Quant, serum/plasma
Test Mnemonic
SBUP
CPT Codes
- 80348 - QTY (1)
- G0480 - QTY (1)
Includes
- Buprenorphine
- Norbuprenorphine
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tubes; Remove serum from cells ASAP or within 2 hours of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | Potassium oxalate/sodium fluoride (Gray) | Refrigerated | Do not use plasma separator tubes; Remove plasma from cells ASAP or within 2 hours of collection. | |
| 2 mL | Plasma | Sodium heparin (Green) | Refrigerated | Do not use plasma separator tubes; Remove plasma from cells ASAP or within 2 hours of collection. | |
| 2 mL | Plasma | EDTA (Lavender) | Refrigerated | Do not use plasma separator tubes; Remove plasma from cells ASAP or within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 1 week |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 3 years (Avoid repeated freeze/thaw cycles) |
Days Performed
Tue, Fri
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
Reference Range
| Buprenorphine Serum/Plasma | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 1 | ng/mL | |
| Norbuprenorphine, Serum/Plasma | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 1 | ng/mL |
Special Info
This test is a reflex from Drug Screen 9 Panel, Serum or Plasma (DRGSC9). This test is New York DOH approved.
Clinical Info
Positive Cutoff: 1 ng/mL. The presence of metabolites(s) without parent drug may indicate use of parent drug during the prior week. The absence of expected drug(s) and/or metabolite(s) may indicate noncompliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive.
Clinical Limitation
For medical purposes only; not valid for forensic use.