Chlorpromazine, Quant
Test Mnemonic
CLORPR
CPT Codes
- 80342 - QTY (1)
- G0480 - QTY (1)
Aliases
- Largactil
- Ormazine
- Thorazine
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Frozen | Predose (trough) draw - At steady state concentration. Do NOT draw separator tubes. Remove serum from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | EDTA (Lavender) | Frozen | Predose (trough) draw - At steady state concentration. Do NOT draw separator tubes. Remove plasma from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. | |
| 2 mL | Plasma | Sodium or Lithium heparin (Green) | Frozen | Predose (trough) draw - At steady state concentration. Do NOT draw separator tubes. Remove plasma from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. | |
| 2 mL | Plasma | Potassium oxalate/sodium fluoride (Gray) | Frozen | Predose (trough) draw - At steady state concentration. Do NOT draw separator tubes. Remove plasma from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: Unacceptable |
| Frozen | After separation from cells: 14 days |
| Refrigerated | After separation from cells: 14 days |
Days Performed
Mon
Turnaround Time
9 - 10 days
Methodology
| Name | Description |
|---|---|
| Quantitative Liquid Chromatography - Tandem Mass Spectrometry |
Reference Range
| Chlorpromazine | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 30 - 300 | ng/mL | Critical | > or = 600 | ng/mL |
Special Info
Draw trough specimen before the next dose at steady state concentration. Whole blood, gel separator tubes, hemolyzed samples, citrate (light blue) tube, and tubes with SPS or ACD (yellow) solution will be rejected.
Clinical Info
Chlorpromazine is a neuroleptic drug indicated for the treatment of schizophrenia, psychotic disorders and intractable hiccup. Chlorpromazine should not be used in patients who have epilepsy, Parkinson’s disease, hypoparathyroidism, myasthenia gravis, and prostatic hypertrophy. Adverse effects may include drowsiness, hypotension, agranulocytosis, cardiac abnormalities, seizures and rare life-threatening effects, such as phenothiazine sudden death syndrome, and neuroleptic malignant syndrome.