Hirsutism Evaluation Panel | Cleveland Clinic Laboratories

Hirsutism Evaluation Panel Print

Test Mnemonic

HIRSUT

CPT Codes

82157 - QTY (1)
84403 - QTY (1)
82627 - QTY (1)
84270 - QTY (1)

Includes

Testosterone
Testosterone, Free
Sex Hormone Binding Globulin
Androstenedione
Dehydroepiandrosterone Sulfate

Performing Laboratory

ARUP

FDA Category

Laboratory Developed Test

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
2.5 mL	Serum	SST (Gold)		Frozen	Separate serum from cells ASAP or within 2 hours of collection.

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
1.5 mL

Stability

Environmental Condition	Description
Frozen	After separation from cells: 2 months
Ambient	After separation from cells: 2 hours
Refrigerated	After separation from cells: 48 hours

Days Performed

Sun - Sat

Turnaround Time

2 - 6 days

Methodology

Name	Description
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Electro Chemiluminescence Immunoassay (ECLIA)
Quantitative Chemiluminescent Immunoassay

Reference Range

Androstenedione
Sex	Age From	Age To	Type	Range	Range Unit
				Female, Premature Infants, 26-28 weeks-Day 4: 0.92 - 2.82 ng/mL
				Male, Premature Infants, 26-28 weeks-Day 4: 0.92 - 2.82 ng/mL
				Male, Tanner Stage I: 0.04 - 0.32 ng/mL
				Male, Tanner Stage II: 0.08 - 0.48 ng/mL
				Male, Tanner Stage III: 0.14 - 0.87 ng/mL
				Male, Premature Infants, 31-35 weeks-Day 4: 0.80 - 4.46 ng/mL
				Female, Tanner Stage IV- V: 0.35 - 2.05 ng/mL
				Female, Premature Infants, 31-35 weeks-Day 4: 0.80 - 4.46 ng/mL
				Female, Tanner Stage III: 0.37 - 2.24 ng/mL
				Female, Pre-menopaual: 0.26 - 2.14 ng/mL
				Female, Post-menopaual: 0.13 - 0.82 ng/mL
				Female, Tanner Stage I: 0.05 - 0.51 ng/mL
				Female, Tanner Stage II: 0.15 - 1.37 ng/mL
				Male, Tanner Stage IV-V: 0.27 - 1.07 ng/mL
Male	8 Years	9 Years	Normal	0.03 - 0.30	ng/mL
Male	1 Days	7 Days	Normal	0.20 - 2.90	ng/mL
Male	8 Days	30 Days	Normal	0.18 - 0.80	ng/mL
Male	1 Months	5 Months	Normal	0.06 - 0.68	ng/mL
Male	6 Months	24 Months	Normal	0.03 - 0.15	ng/mL
Male	2 Years	3 Years	Normal	< 0.11	ng/mL
Male	4 Years	5 Years	Normal	0.02 - 0.17	ng/mL
Male	6 Years	7 Years	Normal	0.01 - 0.29	ng/mL
Male	10 Years	11 Years	Normal	0.07 - 0.39	ng/mL
Male	12 Years	13 Years	Normal	0.10 - 0.64	ng/mL
Male	14 Years	15 Years	Normal	0.18 - 0.94	ng/mL
Male	16 Years	17 Years	Normal	0.30 - 1.13	ng/mL
Male	18 Years	39 Years	Normal	0.33 - 1.34	ng/mL
Male	40 Years	99 Years	Normal	0.23 - 0.89	ng/mL
Female	10 Years	11 Years	Normal	0.09 - 1.23	ng/mL
Female	1 Days	7 Days	Normal	0.20 - 2.90	ng/mL
Female	8 Days	30 Days	Normal	0.18 - 0.80	ng/mL
Female	1 Months	5 Months	Normal	0.06 - 0.68	ng/mL
Female	6 Months	24 Months	Normal	< 0.15	ng/mL
Female	2 Years	3 Years	Normal	< 0.16	ng/mL
Female	4 Years	5 Years	Normal	0.02 - 0.21	ng/mL
Female	6 Years	7 Years	Normal	0.02 - 0.28	ng/mL
Female	8 Years	9 Years	Normal	0.04 - 0.42	ng/mL
Female	12 Years	13 Years	Normal	0.24 - 1.73	ng/mL
Female	14 Years	15 Years	Normal	0.39 - 2.00	ng/mL
Female	16 Years	17 Years	Normal	0.35 - 2.12	ng/mL
Female	18 Years	39 Years	Normal	0.26 - 2.14	ng/mL
Female	40 Years	99 Years	Normal	0.13 - 0.82	ng/mL
Dehydroepiandrosterone Sulfate
Sex	Age From	Age To	Type	Range	Range Unit
Female	Days	6 Days	Normal	108 - 607	ug/dL
Female	7 Days	30 Days	Normal	32 - 431	ug/dL
Female	25 Years	34 Years	Normal	99 - 340	ug/dL
Female	1 Months	5 Months	Normal	3 - 124	ug/dL
Female	6 Months	35 Months	Normal	0 - 29	ug/dL
Female	3 Years	6 Years	Normal	0 - 47	ug/dL
Female	7 Years	9 Years	Normal	5 - 94	ug/dL
Female	10 Years	14 Years	Normal	22 - 255	ug/dL
Female	15 Years	19 Years	Normal	63 - 373	ug/dL
Female	20 Years	24 Years	Normal	148 - 407	ug/dL
Female	35 Years	44 Years	Normal	61 - 337	ug/dL
Female	45 Years	54 Years	Normal	35 - 256	ug/dL
Female	55 Years	64 Years	Normal	19 - 205	ug/dL
Female	65 Years	74 Years	Normal	9 - 246	ug/dL
Female	75 Years	99 Years	Normal	12 - 154	ug/dL
Male	25 Years	34 Years	Normal	160 - 449	ug/dL
Male	6 Months	35 Months	Normal	0 - 33	ug/dL
Male	3 Years	6 Years	Normal	0 - 44	ug/dL
Male	7 Years	9 Years	Normal	5 - 115	ug/dL
Male	10 Years	14 Years	Normal	22 - 332	ug/dL
Male	15 Years	19 Years	Normal	88 - 483	ug/dL
Male	20 Years	24 Years	Normal	211 - 492	ug/dL
Male	35 Years	44 Years	Normal	89 - 427	ug/dL
Male	7 Days	30 Days	Normal	32 - 431	ug/dL
Male	45 Years	54 Years	Normal	44 - 331	ug/dL
Male	55 Years	64 Years	Normal	52 - 295	ug/dL
Male	65 Years	74 Years	Normal	34 - 249	ug/dL
Male	75 Years	99 Years	Normal	16 - 123	ug/dL
Male	1 Months	5 Months	Normal	3 - 124	ug/dL
Male	Days	6 Days	Normal	108 - 607	ug/dL
				Male, Tanner Stage I: 7 - 209 ug/dL
				Male, Tanner Stage II: 28 - 260 ug/dL
				Male, Tanner Stage III: 39 - 390 ug/dL
				Female, Tanner Stage IV & V: 65 - 371 ug/dL
				Female, Tanner Stage I: 7 - 126 ug/dL
				Female, Tanner Stage II: 13 - 241 ug/dL
				Female, Tanner Stage III: 32 - 446 ug/dL
				Male, Tanner Stage IV & V: 81 - 488 ug/dL
Sex Hormone Binding Globulin
Sex	Age From	Age To	Type	Range	Range Unit
Female			Normal	Tanner Stage I: 30 - 173	nmol/L
Female			Normal	Tanner Stage II: 16 - 127	nmol/L
Female	50 Years	99 Years	Normal	17 - 125	nmol/L
Female	18 Years	49 Years	Normal	25 - 122	nmol/L
Female	16 Years	17 Years	Normal	19 - 145	nmol/L
Female	13 Years	15 Years	Normal	11 - 120	nmol/L
Female	10 Years	12 Years	Normal	17 - 155	nmol/L
Female	7 Years	9 Years	Normal	35 - 170	nmol/L
Female	4 Years	6 Years	Normal	55 - 170	nmol/L
Female	1 Years	3 Years	Normal	60 - 190	nmol/L
Female	31 Days	364 Days	Normal	60 - 215	nmol/L
Female	1 Days	30 Days	Normal	14 - 60	nmol/L
Female			Normal	Tanner Stage V: 23 - 165	nmol/L
Female			Normal	Tanner Stage IV: 14 - 151	nmol/L
Female			Normal	Tanner Stage III: 12 - 98	nmol/L
Male			Normal	Tanner Stage II: 22 - 169	nmol/L
Male	18 Years	49 Years	Normal	17 - 56	nmol/L
Male	16 Years	17 Years	Normal	10 - 60	nmol/L
Male	13 Years	15 Years	Normal	13 - 140	nmol/L
Male	10 Years	12 Years	Normal	23 - 160	nmol/L
Male	7 Years	9 Years	Normal	28 - 190	nmol/L
Male	4 Years	6 Years	Normal	45 - 175	nmol/L
Male	1 Years	3 Years	Normal	50 - 180	nmol/L
Male	31 Days	364 Days	Normal	70 - 250	nmol/L
Male	1 Days	30 Days	Normal	13 - 85	nmol/L
Male			Normal	Tanner Stage V: 11 - 71	nmol/L
Male			Normal	Tanner Stage IV: 11 - 60	nmol/L
Male			Normal	Tanner Stage III: 13 - 104	nmol/L
Male			Normal	Tanner Stage I: 26 - 186	nmol/L
Male	50 Years	99 Years	Normal	19 - 76	nmol/L
Testosterone
Sex	Age From	Age To	Type	Range	Range Unit
Female			Normal	Newborn: 20 - 64	ng/dL
Female	12 Years	13 Years	Normal	6 - 50	ng/dL
Female	14 Years	15 Years	Normal	6 - 52	ng/dL
Female	16 Years	17 Years	Normal	9 - 58	ng/dL
Female	18 Years	39 Years	Normal	9 - 55	ng/dL
Female	40 Years	59 Years	Normal	9 - 55	ng/dL
Female	60 Years	99 Years	Normal	5 - 32	ng/dL
Female	8 Years	9 Years	Normal	1 - 11	ng/dL
Female	10 Years	11 Years	Normal	3 - 32	ng/dL
Female			Normal	Postmenopausal: 5 - 32	ng/dL
Female			Normal	Premature (26 - 28 weeks): 5 - 16	ng/dL
Female			Normal	Premature (31 - 35 weeks): 5 - 22	ng/dL
Female			Normal	Premenopausal (Greater than 18 years): 9 - 55	ng/dL
Female			Normal	Tanner Stage I: 2 -17	ng/dL
Female			Normal	Tanner Stage II: 5 - 40	ng/dL
Female			Normal	Tanner Stage III: 10 - 63	ng/dL
Female			Normal	Tanner Stage IV - V: 11 - 62	ng/dL
Female	1 Months	5 Months	Normal	Less than 20	ng/dL
Female	6 Months	24 Months	Normal	Less than 9	ng/dL
Female	2 Years	3 Years	Normal	Less than 20	ng/dL
Female	4 Years	5 Years	Normal	Less than 30	ng/dL
Female	6 Years	7 Years	Normal	Less than 7	ng/dL
Male			Normal	Tanner Stage III: 10 - 851	ng/dL
Male			Normal	Newborn: 75 - 400	ng/dL
Male			Normal	Premature (26 - 28 weeks): 59 - 125	ng/dL
Male			Normal	Premature (31- 35 weeks): 37 - 198	ng/dL
Male			Normal	Tanner Stage I: 2 -15	ng/dL
Male			Normal	Tanner Stage II: 3 - 303	ng/dL
Male			Normal	Tanner Stage IV - V: 162 - 847	ng/dL
Male	1 Months	5 Months	Normal	14 - 363	ng/dL
Male	6 Months	24 Months	Normal	Less than 37	ng/dL
Male	2 Years	3 Years	Normal	Less than 15	ng/dL
Male	4 Years	5 Years	Normal	Less than 19	ng/dL
Male	6 Years	7 Years	Normal	Less than 13	ng/dL
Male	8 Years	9 Years	Normal	2 - 8	ng/dL
Male	10 Years	11 Years	Normal	2 - 165	ng/dL
Male	12 Years	13 Years	Normal	3 - 619	ng/dL
Male	14 Years	15 Years	Normal	31 - 733	ng/dL
Male	16 Years	17 Years	Normal	158 - 826	ng/dL
Male	18 Years	39 Years	Normal	300 - 1080	ng/dL
Male	40 Years	59 Years	Normal	300 - 890	ng/dL
Male	60 Years	99 Years	Normal	300 - 720	ng/dL
			Normal
			Normal	>/=1.00
			Normal	2.22
			Normal	<>6.00
			Normal	=/<33
			Normal	=/>66
				=/<7.50
				>/=10.00

			Urgent
			Urgent	<>3.00
			Urgent	>6 or <7
			Critical	>/<4.00
			Critical	<>3.00
			Critical	>/5.00
Testosterone, Free
Sex	Age From	Age To	Type	Range	Range Unit
Female			Normal	Postmenopausal: 0.6 - 3.8	pg/mL
Female	41 Years	51 Years	Normal	1.1 - 5.8	pg/mL
Female	31 Years	40 Years	Normal	1.3 - 9.2	pg/mL
Female			Normal	Tanner Stage I: Less than 2.2	pg/mL
Female	18 Years	30 Years	Normal	0.8 - 7.4	pg/mL
Female	16 Years	17 Years	Normal	1.2 - 9.9	pg/mL
Female	14 Years	15 Years	Normal	1.2 - 7.5	pg/mL
Female	12 Years	13 Years	Normal	0.9 - 6.8	pg/mL
Female	10 Years	11 Years	Normal	0.1 - 3.5	pg/mL
Female	7 Years	9 Years	Normal	0.6 - 1.8	pg/mL
Female	1 Years	6 Years	Normal	Less than 0.6	pg/mL
Female			Normal	Tanner Stage V: 0.8 - 9.2	pg/mL
Female			Normal	Tanner Stage IV: 1.1 - 15.5	pg/mL
Female			Normal	Tanner Stage III: 1.3 - 7.5	pg/mL
Female			Normal	Tanner Stage II: 0.4 - 4.5	pg/mL
Male	16 Years	17 Years	Normal	38.0 - 173.0	pg/mL
Male	14 Years	15 Years	Normal	3.0 - 138.0	pg/mL
Male	12 Years	13 Years	Normal	0.5 - 98.0	pg/mL
Male	10 Years	11 Years	Normal	0.1 - 6.3	pg/mL
Male	7 Years	9 Years	Normal	0.1 - 0.9	pg/mL
Male	1 Years	6 Years	Normal	Less than 0.6	pg/mL
Male			Normal	Tanner Stage V: 41.0 - 239.0	pg/mL
Male			Normal	Tanner Stage IV: 35.0 - 169.0	pg/mL
Male			Normal	Tanner Stage III: 1.0 - 98.0	pg/mL
Male			Normal	Tanner Stage II: 0.3 - 21.0	pg/mL
Male			Normal	Tanner Stage I: Less than or equal to 3.7	pg/mL
Male	18 Years	99 Years	Normal	47.0 - 244.0	pg/mL

Special Info

Separate serum from cells ASAP or within 2 hours of collection. This test is New York DOH approved.

Clinical Info

Aids in the detection and subclassification of hyperandrogenism. Most useful in women and children with moderate/severe hirsutism of any degree when it is sudden in onset or rapidly progressive.