MAG Antibodies, IgM and SGPG Antibodies, IgM
Test Mnemonic
MASGPG
CPT Codes
- 83516 - QTY (2)
Aliases
- Myelin Associated Glycoprotein Abs,
- IgM & Sulfate-3-Glucuronyl Paragloboside Abs, IgM
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.1 mL | Separate serum from cells ASAP or within 2 hours of collection |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 days |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year |
Days Performed
Tue
Turnaround Time
2 - 9 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| Myelin Associated Glycoprotein (MAG) Ab, IgM | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| MAG Antibody, IgM: < 1000 Titer Units | |||||
| SGPG Antibody, IgM | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| SGPG Antibody, IgM: < 1.00 IV |
Special Info
Separate serum from cells ASAP or within 2 hours of collection.
Clinical Info
Detection of IgM antibody against myelin-associated glycoprotein(MAG) suggests active demyelination in peripheral neuropathy. The possiblity of MAG antibody involvement in a suspected neropathy may essentially be ruled out if a MAG IgM negative result is obtained. The majority of sulfate-3-glucuronyl paragloboside(SPGP) IgM positive sera will show reactivity against MAG. Patients who are SGPG IgM positive and MAG IgM negative may have multi-focal motor neuropathy with conduction block.