PSA
Test Mnemonic
PSA
CPT Codes
- 84153 - QTY (1)
LOINC ®
2857-1
Aliases
- Prostate Specific Antigen, Diagnostic
- Ultra Sensitive PSA
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | Lithium heparin PST (Lt. Green) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 5 days |
| Frozen | 6 months |
Days Performed
Sun - Sat
Turnaround Time
8 hours
Methodology
| Name | Description |
|---|---|
| Electro Chemiluminescence Immunoassay (ECLIA) |
Reference Range
| PSA | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Male | Normal | <2.6 | ng/mL | Note: See Special Info section |
Special Info
For an individual patient, the significance of a PSA level should be interpreted in a broad clinical context, including age, race, family history, digital rectal exam, prostate size, results of prior testing (prostate biopsy, free PSA, PCA3), and use of 5-alpha reductase inhibitors. Considering the high incidence of asymptomatic cancer in the general population that may not pose an ultimate risk to the patient, the decision to recommend urological evaluation or prostate biopsy should be individualized after considering all of these factors. Reference: Punglia S, Rinaa, M.D., M.P.H., D'Amico V, Anthony, M.D., Ph.D., Catalona J, William, M.D., Roehl A, Kimberly, M.P.H., Kuntz M., Karen, Sc.D. Effect of Verification Bias on Screening for Prostate Cancer Measurement of Prostate-Specific Antigen. N Engl J Med 2003;349:335-42. Add-ons will only be accepted from the emergency department providing an unopened/unprocessed tube is available for testing.
Clinical Info
Evaluation and monitoring of patients with prostatic carcinoma.