RPR
Test Mnemonic
RPR
CPT Codes
- 86592 - QTY (1)
LOINC ®
20507-0
Aliases
- Rapid Plasma Reagin Test (RPR)
- Syphilis serology RPR
Includes
- RPR
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | SST (Gold) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 day |
| Refrigerated | 7 days |
| Frozen | 14 days |
Days Performed
Sun - Sat
Turnaround Time
1 - 2 days
Methodology
| Name | Description |
|---|---|
| Latex Particle Agglutination (LPA) |
Reference Range
Special Info
If reactive, then RPR Quant Titer will be performed and billed. When a reactive specimen is found, Ohio State law requires completion of an Ohio Department of Health confidential report form.
Clinical Info
Rapid Plasma Reagin (RPR) is a semi-quantitative non-treponemal test that is only used when syphilis screen (i.e., treponemal) test is positive/reactive. RPR is also used for treatment follow up of treponemal infections mainly venereal syphilis. RPR may be reactive due to a range of other causes, certain infections (HIV, tuberculosis, malaria, etc.), anti-phospholipid syndrome, endocarditis, and malignancies among others. Clinical correlation is required.