Topiramate
Test Mnemonic
TOPIR
CPT Codes
- 80201 - QTY (1)
LOINC ®
17713-9
Aliases
- Topamax
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tubes. Separate serum from cells ASAP or within 2 hours of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | Sodium or Lithium heparin (Green) | Refrigerated | Do not use plasma separator tubes. Separate plasma from cells ASAP or within 2 hours of collection. | |
| 1 mL | Plasma | EDTA (Lavender) | Refrigerated | Do not use plasma separator tubes. Separate plasma from cells ASAP or within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | After separation from cells: 4 weeks |
| Refrigerated | After separation from cells: 1 week |
Days Performed
Mon - Fri
Turnaround Time
0 - 3 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Reference Range
| Topiramate | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 5.0 - 20.0 | ug/mL |
Special Info
Do not use serum separator tubes. Separate serum from cells ASAP or within 2 hours of collection.
Clinical Info
Monitor therapeutic administration of topiramate. Therapeutic range not well established. The proposed therapeutic range for seizure control is 5-20 ug.mL. Pharmacokinetics varies widely, particularly with co-medications, age and/or compromised renal function.