5- Flucytosine, Antibiotic Assay, Serum




Test Mnemonic

FLCYT

CPT Codes

  • 80299 - QTY (1)

Aliases

  • 5-Flucytosine
  • 5-Fluorocytosine
  • Ancobon
  • Antimicrobial Assay, 5-Flucytosine
  • Fluorocytosine

Includes

  • 5-Flucytosine, S

Performing Laboratory

Mayo Clinic Dpt of Lab Med & Pathology

FDA Category

Laboratory Developed Test


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLSerumNo additive (Red) RefrigeratedTrough specimen should be collected immediately prior to next dose. Peak level should be collected 1 to 2 hours after oral dose, or 30 minutes after IV infusion. Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.3 mL     

Stability

Environmental Condition Description
Ambient28 days
Refrigerated28 days
Frozen28 days

Days Performed

Tue, Thu

Turnaround Time

4 - 9 days

Methodology

Name Description
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) 

Reference Range

5-FLUCYTOSINE, SERUM
Sex Age From Age To Type Range Range Unit
       NormalTherapeutic: Peak >25.0 (difficult infections may require higher concentrations)mcg/mL
       NormalToxic: Peak >100.0mcg/mL

Special Info

This test is New York state approved.

Clinical Info

This test is useful for monitoring serum concentration during therapy, evaluating potential toxicity, and evaluating patient compliance.