Chlamydia Antibody Panel, IgG
Test Mnemonic
CHLAMG
CPT Codes
- 86631 - QTY (3)
Includes
- C. trachomatis IgG Titer
- C. pneumoniae IgG Titer
- C. psittaci IgG Titer
Performing Laboratory
ARUP
FDA Category
Analyte Specific Reagent
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells within 2 hours of collection and transfer into a standard aliquot tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Label specimens plainly as acute or convalescent. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Separate serum from cells within 2 hours of collection and transfer into a standard aliquot tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Label specimens plainly as acute or convalescent. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.4 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (avoid repeated freeze/thaw cycles) |
Days Performed
Mon - Sat
Turnaround Time
2 - 4 days
Methodology
| Name | Description |
|---|---|
| Semi-Quantitative Indirect Fluorescent Antibody |
Reference Range
| C. pneumoniae IgG Titer | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:64 | |||||
| C. psittaci IgG Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:64 | |||||
| C. trachomatis IgG Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:64 |
Special Info
Contaminated, hemolyzed, or hyperlipemic sera will be rejected. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent. This test is New York DOH approved.
Clinical Info
Differentiate between Chlamydophila species (C. psittaci, C. pneumoniae). Because of cross-reactivity, a C. pneumoniae-specific reaction will exhibit titers two-fold or greater than C. trachomatis or C. psittaci serology. Limited value in the diagnosis of most oculogenital (eg, eyes, genitalia) chlamydial infections. The Chlamydia antibody test contains both species- and genus-specific antigens, and serological cross-reactions may be seen in both acute and convalescent samples (less than 1:128). A C. pneumoniae-specific reaction will exhibit titers twofold or greater than titers observed with C. trachomatis or C. psittaci serology. Any IgG titer may indicate past exposure to that particular species. IgG titers in recently infected individuals are typically greater than or equal to 1:512. The Chlamydia microimmunofluorescent assay slides utilize C. psittaci, C. pneumoniae, and nine serotypes of C. trachomatis. The LGV strains of C. trachomatis are not included in this assay.