AFP L3% & Total, Hepatocellular Carcinoma
Test Mnemonic
AFPL3
CPT Codes
- 82107 - QTY (1)
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Frozen | Remove serum from cells within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 8 hours |
| Refrigerated | After separation from cells: 5 days |
| Frozen | After separation from cells: 3 months (Avoid multiple freeze/thaw cycles) |
Days Performed
Mon, Thu
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Quantitative Liquid Chromatography/Immunoassay |
Reference Range
| Alpha fetoprotein, L3% | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 0 - 9.9 | % | |
| Alpha fetoprotein, Total | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 0 - 15 | ng/mL |
Special Info
This test is New York DOH approved. Plasma specimens will be rejected.
Clinical Info
The purpose of this test is surveillance and monitoring of hepatocellular carcinoma. The µTASWako method is used and results cannot be used interchangeably with any other assay methods or kits. The AFP L3 Percent assay is intended as a risk assessment for the development of hepatocellular carcinoma in patients with chronic liver diseases. Patients with elevated serum AFP-L3 percent should be more intensely evaluated for evidence of hepatocellular carcinoma since elevated values have been shown to be associated with a seven-fold increase in the risk for developing hepatocellular carcinoma within 21 months. Results cannot be interpreted as absolute evidence of the presence or absence of malignant disease. For pregnant females, the result is not interpretable as a tumor marker.